Diagnostic Testing, Research & Education

The Immunogenetics and Transplantation Laboratory (ITL) provides specialized diagnostic services for allogeneic transplantation and conducts related research. The laboratory provides support for blood, bone marrow, kidney, pancreas, liver, heart, lung, small bowel, and cornea transplantation. The Immunogenetics and Transplantation Laboratory is a national reference laboratory, a referee laboratory for the ASHI proficiency testing program, a NMDP contract laboratory, a core laboratory for the NIH Immune Tolerance Network, and a participant in several national clinical trials. The laboratory also conducts basic research and provides educational programs for health care professionals. The laboratory is not-for-profit and is owned and operated by the University of California, San Francisco.

Recent Publications

Lin L, Ma C, Wei B, Aziz N, Rajalingam R, Yusung S, Erlich HA, Trachtenberg EA, Targan SR, McGovern DP, Heath JR, Braun J
Human NK cells licensed by killer Ig receptor genes have an altered cytokine program that modifies CD4+ T cell function.
Journal of immunology (Baltimore, Md. : 1950), Jul-15-2014; 1932: 940-9.  Epub 2014 Jun 16.
Dvorak CC, Gilman AL, Horn B, Jaroscak J, Dunn EA, Baxter-Lowe LA, Cowan MJ
Clinical and immunologic outcomes following haplocompatible donor lymphocyte infusions.
Bone marrow transplantation, Dec-01-2009; 4412: 805-12.  Epub 2009 May 04.
Kurtzberg J, Prasad VK, Carter SL, Wagner JE, Baxter-Lowe LA, Wall D, Kapoor N, Guinan EC, Feig SA, Wagner EL, Kernan NA, Kernan NA
Results of the Cord Blood Transplantation Study (COBLT): clinical outcomes of unrelated donor umbilical cord blood transplantation in pediatric patients with hematologic malignancies.
Blood, Nov-15-2008; 11210: 4318-27.  Epub 2008 Aug 21.
John J. Garcia, Lan T. Vu, Peter Stock, Lee Ann Baxter Lowe.
Efficacy of Labscreen Reagents for Detection of Post Transplant HLA Antibodies.
Human Immunology, Oct-16-2008; [In Press] 69Supplement 1: S36.
Williams TM, Winden T, Setterholm M, Vierra-Green CA, Spellman S, Flesch S, Awdeh Z, Baxter-Lowe LA, Begovich AB, Fernandez-Vina M, Hegland J, Hurley CK, Johnson D, Noreen H, Salazar M, Schmeckpeper B, Yunis EJ
Strategies and technical challenges in allele level Class II typing in 2578 bone marrow transplantation donor-recipient pairs.
Human immunology, 694-5: 227-34.  Epub 2008 Apr 25.
Lee SJ, Klein J, Haagenson M, Baxter-Lowe LA, Confer DL, Eapen M, Fernandez-Vina M, Flomenberg N, Horowitz M, Hurley CK, Noreen H, Oudshoorn M, Petersdorf E, Setterholm M, Spellman S, Weisdorf D, Williams TM, Anasetti C
High-resolution donor-recipient HLA matching contributes to the success of unrelated donor marrow transplantation.
Blood, Dec-15-2007; 11013: 4576-83.  Epub 2007 Sep 4.
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